Sites are not accessible: Error HTTP 500.0 - Internal Server Error

Symptoms

• Trying to access a domain website shows the following error:

  HTTP Error 500.0 - Internal Server Error
  C:\Program Files\Parallels\Plesk\Additional\PleskPHP72\php-cgi.exe - The FastCGI process exited unexpectedly

• Repairing permissions for C:\Windows\Temp has no effect

  C:\Users\Administrador>plesk repair --directory-permissions -directory "C:\Windows\Temp"
  Permissions were fixed for directory "C:\Windows\Temp"

• Disabling opcache for the PHP version reported in the error fixes the problem

  

Cause

One or more necessary cache files in C:\Windows\Temp are corrupted.

Resolution

1. Connect to the server over RDP

2. Remove all files from C:\Windows\Temp

3. Restart IIS using a Command Prompt

   C:\>iisreset