Plesk shows error: ODBC code #IM003: Specified driver could not be loaded due to system error 5 (MySQL ODBC 3.51 Driver)

Symptoms

• When changing a PHP handler of a domain or logging in to Plesk as a customer, the following error is displayed in a browser:

  PLESK_INFO: Internal error:
  ODBC error #IM003: Specified driver could not be loaded due to system error 5: Access is denied. (MySQL ODBC 3.51 Driver, C:\Program Files (x86)\MySQL\Connector ODBC 3.51\myodbc3.dll).ODBC error #IM003:
  Message ODBC error #IM003: Specified driver could not be loaded due to system error 5: Access is denied. (MySQL ODBC 3.51 Driver, C:\Program Files (x86)\MySQL\Connector ODBC 3.51\myodbc3.dll).ODBC error #IM003:
  File aps_php.php
  Line 12522
  Type Exception

• Some of websites could not work due to the handler mapping error.

Cause

An installation of MySQL ODBC 3.51 Driver is corrupted.

Resolution

1. Connect to a Plesk server via RDP.

2. Remove MySQL ODBC 3.51 Driver:

   2.1. Open Control Panel from Windows Start and navigate to Programs and Features.

   2.2. Select MySQL Connector/ODBC 3.51 and click uninstall.

3. Start a command prompt as an Administrator and run the command:

   C:\> plesk installer --select-release-current --install-component mysql-odbc