Plesk shows error: ODBC code #IM003: Specified driver could not be loaded due to system error 5 (MySQL ODBC 3.51 Driver)

Symptoms

• When changing a PHP handler of a domain or logging in to Plesk as a customer, the following error is displayed in a browser:

  PLESK_INFO: Internal error:
  Message ODBC error #IM003: Specified driver could not be loaded due to system error 5: Access is denied. (MySQL ODBC 3.51 Driver, C:\Program Files (x86)\MySQL\Connector ODBC 3.51\myodbc3.dll).ODBC error #IM003:
  File aps_php.php
  Line 12522
  Type Exception

• Some websites do not work due to the handler mapping error.

Cause

The installation of MySQL ODBC 3.51 Driver is corrupted.

Resolution

1. Connect to the Plesk server via RDP.

2. Remove MySQL ODBC 3.51 Driver:

   2.1. Open Control Panel from Windows Start and navigate to Programs and Features.

   2.2. Select MySQL Connector/ODBC 3.51 and click uninstall.

3. Start a command prompt as an Administrator and run the following command to install MySQL ODBC 3.51 Driver:

   C:\> plesk installer --select-release-current --install-component mysql-odbc