NodeJS application does not work if the subscription's user is enabled in the CageFS.
Apache error log /var/log/httpd/error_log may contain the following error:
Cannot checkout session because a spawning error occurred. The identifier of the error is 912c3777. Please see earlier logs for details about the error.
Passenger server creates a socket to communicate with NodeJS application (e.g. /tmp/passenger.UR4xOGA/apps.s/node.36hbwz)
Whilst NodeJS application works inside CageFS and has its own private /tmp. Thus, it cannot access to the socket created outside CageFS.
Plesk bug #PPPM-6664
The issue will be fixed in one of Plesk updates.